Sophia S Sheikh

Sophia S Sheikh, MD

Associate Professor; Medical Director, Florida/USVI Poison Information Center – Jacksonville

Department: Emergency Medicine – Jacksonville
Business Phone: (904) 244-4986
Business Email: sophia.sheikh@jax.ufl.edu

About Sophia S Sheikh

Sophia Sheikh, MD, received her degree from the University of Alabama at Birmingham School of Medicine and completed her residency training at the University of Florida College of Medicine – Jacksonville. She then pursued further training in the field of medical toxicology at the joint program offered by Emory University and the Centers for Disease Control and Prevention in Atlanta, Georgia. While learning the clinical aspects of medical toxicology, she also learned principles related to public health surveillance, epidemiology, public health and disease prevention. In addition to toxicology, she also has an interest in emergency department pain management. She is a sub-investigator on a patient safety grant working on improving pain management and education in acute care settings. She authored several publications and presented lectures nationally on these topics. Currently, she is a clinical associate professor at the University of Florida College of Medicine – Jacksonville.

Additional Positions:
Associate Professor of Emergency Medicine
2021 – Current · University of Florida
Assistant Professor of Emergency Medicine
2012 – 2021 · University of Florida

Board Certifications

  • Emergency Medicine
    American Board of Emergency Medicine
  • Medical Toxicology
    American Board of Emergency Medicine

Clinical Profile

Specialties
  • Emergency Medicine
Subspecialties
  • Medical Toxicology

Research Profile

Open Researcher and Contributor ID (ORCID)

0000-0003-1939-3126

Publications

2024
Associations of alcohol and cannabis use with change in posttraumatic stress disorder and depression symptoms over time in recently trauma-exposed individuals.
Psychological medicine. 54(2):338-349 [DOI] 10.1017/S0033291723001642. [PMID] 37309917.
2024
Author Correction: Defining the r factor for post-trauma resilience and its neural predictors
Nature Mental Health. 2(5):627-627 [DOI] 10.1038/s44220-024-00258-6.
2024
Characterizing Utilization and Outcomes of Digoxin Immune Fab for Digoxin Toxicity
Drugs – Real World Outcomes. [DOI] 10.1007/s40801-024-00435-0.
2024
Defining the r factor for post-trauma resilience and its neural predictors
Nature Mental Health. [DOI] 10.1038/s44220-024-00242-0.
2024
Disentangling sex differences in PTSD risk factors
Nature Mental Health. 2(5):605-615 [DOI] 10.1038/s44220-024-00236-y.
2024
Emergency department management of North American snake envenomations.
Emergency medicine practice. 26(Suppl 2):1-44 [PMID] 38350100.
2024
Post-traumatic stress and future substance use outcomes: leveraging antecedent factors to stratify risk.
Frontiers in psychiatry. 15 [DOI] 10.3389/fpsyt.2024.1249382. [PMID] 38525258.
2024
Probing the neurocardiac circuit in trauma and posttraumatic stress
Journal of Psychiatric Research. [DOI] 10.1016/j.jpsychires.2024.06.009.
2024
Sex Differences in Response Inhibition-Related Neural Predictors of Posttraumatic Stress Disorder in Civilians With Recent Trauma.
Biological psychiatry. Cognitive neuroscience and neuroimaging. [DOI] 10.1016/j.bpsc.2024.03.002. [PMID] 38522649.
2023
A pilot study to identify pharmacogenomic and clinical risk factors associated with opioid related falls and adverse effects in older adults
Clinical and Translational Science. 16(11):2331-2344 [DOI] 10.1111/cts.13634. [PMID] 37705211.
2023
Association between microbiome and the development of adverse posttraumatic neuropsychiatric sequelae after traumatic stress exposure
Translational Psychiatry. 13(1) [DOI] 10.1038/s41398-023-02643-8. [PMID] 37980332.
2023
Derivation and Validation of a Brief Emergency Department-Based Prediction Tool for Posttraumatic Stress After Motor Vehicle Collision.
Annals of emergency medicine. 81(3):249-261 [DOI] 10.1016/j.annemergmed.2022.08.011. [PMID] 36328855.
2023
Internal capsule microstructure mediates the relationship between childhood maltreatment and PTSD following adulthood trauma exposure
Molecular Psychiatry. 28(12):5140-5149 [DOI] 10.1038/s41380-023-02012-3. [PMID] 36932158.
2023
Neighborhood Disadvantage and Neural Correlates of Threat and Reward Processing in Survivors of Recent Trauma.
JAMA network open. 6(9) [DOI] 10.1001/jamanetworkopen.2023.34483. [PMID] 37721751.
2023
Prior Sexual Trauma Exposure Impacts Posttraumatic Dysfunction and Neural Circuitry Following a Recent Traumatic Event in the AURORA Study.
Biological psychiatry global open science. 3(4):705-715 [DOI] 10.1016/j.bpsgos.2023.02.004. [PMID] 37881578.
2023
Structural inequities contribute to racial/ethnic differences in neurophysiological tone, but not threat reactivity, after trauma exposure
Molecular Psychiatry. 28(7):2975-2984 [DOI] 10.1038/s41380-023-01971-x. [PMID] 36725899.
2023
Use of serial smartphone-based assessments to characterize diverse neuropsychiatric symptom trajectories in a large trauma survivor cohort
Translational Psychiatry. 13(1) [DOI] 10.1038/s41398-022-02289-y. [PMID] 36609484.
2023
Utility of Wrist-Wearable Data for Assessing Pain, Sleep, and Anxiety Outcomes After Traumatic Stress Exposure.
JAMA psychiatry. 80(3):220-229 [DOI] 10.1001/jamapsychiatry.2022.4533. [PMID] 36630119.
2022
Anxiety sensitivity as a transdiagnostic risk factor for trajectories of adverse posttraumatic neuropsychiatric sequelae in the AURORA study
Journal of Psychiatric Research. 156:45-54 [DOI] 10.1016/j.jpsychires.2022.09.027. [PMID] 36242943.
2022
Characterizing OPRM1 DNA methylation in prescription opioid users with chronic musculoskeletal pain.
Pain reports. 7(6) [DOI] 10.1097/PR9.0000000000001046.
2022
Hippocampal Threat Reactivity Interacts with Physiological Arousal to Predict PTSD Symptoms.
The Journal of neuroscience : the official journal of the Society for Neuroscience. 42(34):6593-6604 [DOI] 10.1523/JNEUROSCI.0911-21.2022. [PMID] 35879096.
2022
Neurocognition after motor vehicle collision and adverse post-traumatic neuropsychiatric sequelae within 8 weeks: Initial findings from the AURORA study.
Journal of affective disorders. 298(Pt B):57-67 [DOI] 10.1016/j.jad.2021.10.104. [PMID] 34800569.
2022
Predicting at-risk opioid use three months after ed visit for trauma: Results from the AURORA study
PLOS ONE. 17(9) [DOI] 10.1371/journal.pone.0273378. [PMID] 36149896.
2022
Prior histories of posttraumatic stress disorder and major depression and their onset and course in the three months after a motor vehicle collision in the AURORA study.
Depression and anxiety. 39(1):56-70 [DOI] 10.1002/da.23223. [PMID] 34783142.
2022
Structural covariance of the ventral visual stream predicts posttraumatic intrusion and nightmare symptoms: a multivariate data fusion analysis
Translational Psychiatry. 12(1) [DOI] 10.1038/s41398-022-02085-8. [PMID] 35941117.
2022
Validating the HELP Survey to Understand Health Disparity Influence on Chronic Pain.
Journal of pain research. 15:545-560 [DOI] 10.2147/JPR.S338669. [PMID] 35228818.
2021
A prospective examination of sex differences in posttraumatic autonomic functioning
Neurobiology of Stress. 15 [DOI] 10.1016/j.ynstr.2021.100384. [PMID] 34485632.
2021
Brain-Based Biotypes of Psychiatric Vulnerability in the Acute Aftermath of Trauma.
The American journal of psychiatry. 178(11):1037-1049 [DOI] 10.1176/appi.ajp.2021.20101526. [PMID] 34645277.
2021
Classification and Prediction of Post-Trauma Outcomes Related to PTSD Using Circadian Rhythm Changes Measured via Wrist-Worn Research Watch in a Large Longitudinal Cohort
IEEE Journal of Biomedical and Health Informatics. 25(8):2866-2876 [DOI] 10.1109/jbhi.2021.3053909.
2021
Comparing Pain Intensity Using the Numeric Rating Scale and Defense and Veterans Pain Rating Scale in Patients Revisiting the Emergency Department.
Cureus. 13(8) [DOI] 10.7759/cureus.17501. [PMID] 34603880.
2021
Development and Validation of a Model to Predict Posttraumatic Stress Disorder and Major Depression After a Motor Vehicle Collision.
JAMA psychiatry. 78(11):1228-1237 [DOI] 10.1001/jamapsychiatry.2021.2427. [PMID] 34468741.
2021
Opioid Overdose Risk in Patients Returning to the Emergency Department for Pain
Pain Medicine. 22(9):2100-2105 [DOI] 10.1093/pm/pnab047. [PMID] 33560418.
2021
Pain after a motor vehicle crash: The role of socio‐demographics, crash characteristics and peri‐traumatic stress symptoms
European Journal of Pain. 25(5):1119-1136 [DOI] 10.1002/ejp.1733.
2021
Prior sleep problems and adverse post-traumatic neuropsychiatric sequelae of motor vehicle collision in the AURORA study
Sleep. 44(3) [DOI] 10.1093/sleep/zsaa200. [PMID] 32975289.
2021
Prognostic neuroimaging biomarkers of trauma-related psychopathology: resting-state fMRI shortly after trauma predicts future PTSD and depression symptoms in the AURORA study
Neuropsychopharmacology. 46(7):1263-1271 [DOI] 10.1038/s41386-020-00946-8. [PMID] 33479509.
2021
Socio-demographic and trauma-related predictors of PTSD within 8 weeks of a motor vehicle collision in the AURORA study
Molecular Psychiatry. 26(7):3108-3121 [DOI] 10.1038/s41380-020-00911-3. [PMID] 33077855.
2021
Thalamic volume and fear extinction interact to predict acute posttraumatic stress severity
Journal of Psychiatric Research. 141:325-332 [DOI] 10.1016/j.jpsychires.2021.07.023. [PMID] 34304036.
2021
The Toxicology Investigators Consortium 2020 Annual Report
Journal of Medical Toxicology. 17(4):333-362 [DOI] 10.1007/s13181-021-00854-3. [PMID] 34535889.
2020
Predicting Pain-Related 30-Day Emergency Department Return Visits in Middle-Aged and Older Adults
Pain Medicine. 21(11):2748-2756 [DOI] 10.1093/pm/pnaa213. [PMID] 32875332.
2020
Socio-demographic and trauma-related predictors of depression within eight weeks of motor vehicle collision in the AURORA study.
Psychological medicine. 1-14 [DOI] 10.1017/S0033291720003773. [PMID] 33118917.
2019
Risk Factors Associated with Emergency Department Recidivism in the Older Adult.
The western journal of emergency medicine. 20(6):931-938 [DOI] 10.5811/westjem.2019.7.43073. [PMID] 31738721.
2018
Emergency department management of North American snake envenomations.
Emergency medicine practice. 20(9):1-26 [PMID] 30130010.
2018
Points & Pearls: Emergency department management of North American snake envenomations.
Emergency medicine practice. 20(19 Suppl):1-2 [PMID] 30179413.
2018
The Expanding Role of Ketamine in the Emergency Department
Drugs. 78(7):727-735 [DOI] 10.1007/s40265-018-0904-8.
2017
Female With Vaginal Spotting.
Annals of emergency medicine. 70(1):e1-e2 [DOI] 10.1016/j.annemergmed.2017.01.012. [PMID] 28645417.
2016
Assessing patient activation and health literacy in the ED.
The American journal of emergency medicine. 34(1):93-6 [DOI] 10.1016/j.ajem.2015.09.045. [PMID] 26508580.
2016
Response to Comments on “Poisonings with Suicidal Intent Aged 0-21 Years Reported to Poison Centers 2003-12”.
The western journal of emergency medicine. 17(1):94-6 [DOI] 10.5811/westjem.2015.12.29429. [PMID] 26823943.
2015
Poisonings with Suicidal Intent Aged 0-21 Years Reported to Poison Centers 2003-12.
The western journal of emergency medicine. 16(4):497-502 [DOI] 10.5811/westjem.2015.5.25459. [PMID] 26265960.
2014
Comparison of Iatrogenic Adverse Drug Events Occurring in Hospital and Community Settings Reported To Three Poison Centers
Clinical Toxicology. 52(7):691-692
2014
Incidents of potential public health significance identified using national surveillance of US poison center data (2008–2012)
Clinical Toxicology. 52(9):958-963 [DOI] 10.3109/15563650.2014.953171. [PMID] 25175899.
2013
Characterizing risk factors for pediatric lamp oil product exposures
Clinical Toxicology. 51(9):871-878 [DOI] 10.3109/15563650.2013.839028. [PMID] 24066734.
2013
Passive Multistate Surveillance for Neutropenia After Use of Cocaine or Heroin Possibly Contaminated With Levamisole
Annals of Emergency Medicine. 61(4):468-474 [DOI] 10.1016/j.annemergmed.2012.10.036.
2012
Do-Not-Resuscitate Orders in Fatal Toxic Exposures: A Poison Center’s Review.
The western journal of emergency medicine. 13(3):294-7 [DOI] 10.5811/westjem.2012.3.11725. [PMID] 22928059.
2012
Exotic venomous snakebite drill
Clinical Toxicology. 50(6):490-496 [DOI] 10.3109/15563650.2012.690882.
2012
Radiological preparedness-awareness and attitudes: A cross–sectional survey of emergency medicine residents and physicians at three academic institutions in the United States
Clinical Toxicology. 50(1):34-38 [DOI] 10.3109/15563650.2011.637047.

Grants

Jul 2023 ACTIVE
Together: Transforming and Translating Discovery to Improve Health
Role: Project Manager
Funding: NATL INST OF HLTH NCATS
Sep 2022 ACTIVE
ToxIC Novel Opioid and Stimulant Exposures (ToxIC NOSE): Development of a Rapid Response Program for Emerging Drugs of Abuse Focusing on Opioids and Stimulants for Enhanced Reporting to the Opioid Response Network (ORN)
Role: Principal Investigator
Funding: AMERICAN COLLEGE OF MEDICAL TOXICOLOGY via AMER ACAD OF ADDICTION PSYCHIATRY
Jul 2022 ACTIVE
Pain Assessment and Management Initiative (PAMI) 4.0
Role: Co-Investigator
Funding: FL MED MALPRACTICE JOINT UNDRWRTNG ASSO
Jan 2022 – Jul 2023
Utilization of Digoxin Immune Fab for Serious and Life-Threatening Digoxin Toxicity
Role: Principal Investigator
Funding: BTG INTERNATIONAL
Nov 2021 – Sep 2022
FDA ACMT COVID-19 ToxIC (FACT) Pharmacovigilance Project
Role: Principal Investigator
Funding: AMERICAN COLLEGE OF MEDICAL TOXICOLOGY via US FOOD AND DRUG ADMN
Oct 2021 – Nov 2023
Randomized, Double-Blinded, Placebo-Controlled Study to Evaluate the Safety, Tolerability, and Efficacy of a Multi-Dose Regimen of Oral Varespladib-Methyl in Subjects Bitten by Venomous Snakes
Role: Principal Investigator
Funding: PREMIER RESEARCH INTERNATIONAL via OPHIREX
Mar 2021 ACTIVE
North American Snake Bite Registry (NASBR)
Role: Principal Investigator
Funding: AMERICAN COLLEGE OF MEDICAL TOXICOLOGY
Sep 2020 – Sep 2022
ToxIC Novel Opioid and Stimulant Exposures (ToxIC NOSE): Development of a Rapid Response Program for Emerging Drugs of Abuse Focusing on Opioids and Stimulants for Enhanced Reporting to the Opioid Response Network (ORN)
Role: Principal Investigator
Funding: AMERICAN COLLEGE OF MEDICAL TOXICOLOGY
Aug 2020 – Feb 2024
Pain Assessment and Management Initiatives Emergency Department Alternatives to Opioids (PAMI ED-ALT)
Role: Principal Investigator
Funding: SUBSTANCE ABUSE MENTAL HLTH SER ADMIN
Jul 2020 – Jul 2022
OR-DRPD-ROF2020: Geospatial Analysis to Predict Pain Outcomes (GAP)
Role: Principal Investigator
Funding: UF RESEARCH
Nov 2019 – Nov 2023
The Aging and Integrative Pain Management Initiative
Role: Principal Investigator
Funding: UF FOUNDATION via FLORIDA BLUE FOUNDATION
Aug 2019 – Jul 2022
Neighborhood of Pain- Health Disparity Influence on Chronic Pain Interference
Role: Co-Investigator
Funding: FOU FOR PHYSICAL MEDICINE & REHABILITATI via ABBVIE FOUNDATION
Mar 2019 – Aug 2022
Pain Assessment and Management Initiative 3.0: Multimodal Approaches to Improve Pain Outcomes and reduce Opioid Risks
Role: Co-Project Director/Principal Investigator
Funding: FL MED MALPRACTICE JOINT UNDRWRTNG ASSO
Jan 2018 – Dec 2019
Development and Validation of a Screening Protocol to Identify Elder Abuse in United States Emergency Departments
Role: Co-Investigator
Funding: UNIV OF NORTH CAROLINA CHAPEL HILL via US DEPT OF JUSTICE NATL INST OF JUSTICE

Education

Medical Toxicology Fellowship
2012 · Emory University School of Medicine
Emergency Medicine Residency
2010 · University of Florida College of Medicine – Jacksonville
Doctor of Medicine
2007 · University of Alabama at Birmingham School of Medicine

Contact Details

Phones:
Business:
(904) 244-4986
Emails:
Addresses:
Business Mailing:
655 West 8th Street
Department of Emergency Medicine
JACKSONVILLE FL 322096511
Business Street:
UF Health Jacksonville
Clinical Center, First Floor
655 West 8th Street
JACKSONVILLE FL 32209